Obama's move drew criticism from Republican contenders in the 2016 presidential race.
"I know [Republicans] don't agree with me on this issue, but I think it was the right move to make and I'm glad the president did it," he said on CNN's "The Situation Room."
Cuba was placed on the state sponsors of terrorism list in 1982 when Havana was busy supporting armed insurgencies in Latin America, during the Cold War between the U.S. and the Soviet Union.
Last December, Obama announced his intent to normalize relations with Cuba, insisting that previous U.S. efforts had failed to topple the governments of Fidel and Raul Castro through diplomatic isolation. Instead, the President argued a new approach of engagement was needed to ease tensions between Washington and Havana.
Almost as soon as the new discussions began, however, Cuban officials complained their nation's placement on the list of state sponsors of terrorism was unfair and outdated.
Last week, the State Department recommended to Obama that Cuba be removed from the list, concluding Havana was no longer a sponsor of terrorist activities abroad.
"Circumstances have changed since 1982, when Cuba was originally designated as a State Sponsor of Terrorism because of its efforts to promote armed revolution by forces in Latin America," Secretary of State John Kerry said in a statement on the President's decision.
"Our Hemisphere, and the world, look very different today than they did 33 years ago," Kerry added.
The most dramatic sign of the improved U.S.-Cuban relationship came last Saturday, whenObama and Raul Castro sat down for an hour long discussion on the sidelines of the Summit of the Americas in Panama. It was the first such meeting between U.S. and Cuban leaders since 1959.
And from Al Jazeera this commentary on the Internet in Cuba. Interesting stuff (that would drive me crazy!):